The most common site of nasopharyngeal carcinoma is

Correct Answer: Fossa of Rosenmuller
Description: The commonest site of origin of nasopharyngeal carcinoma is fossa of Rosenmuller in the lateral wall of the nasopharynx. Tumor can spread to the following areas:- Cranium through foramen lacerum & ovale → cranial nerves involvement (III, IV, V, VI); facial pain, and ophthalmic symptoms. Parapharyngeal space → cranial nerves (IX, X, XI, XII) involvement, Horner's syndrome, Trismus (Pterygoid muscle). Retropharyngeal nodes → Neck pain & stiffness. Eustachian tube → Serous OM. Nose and orbit → Obstruction, epistaxis, proptosis. Cervical nodes → Upper jugular and posterior triangle nodes enlargement. Distant metastasis → Lung, liver, bone. Middle ear → Rarely, tumor grows up the tube into the middle ear.
Category: ENT
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