Which of the following anti-angina drugs act by inhibition of long-chain 3-ketoacyl coenzyme A thiolase?
Correct Answer: Trimetazidine
Description: Trimetazidine Antianginal drug that act by inhibiting mitochondrial long-chain 3-ketoacyl coenzyme A thiolase enzyme. Reduced fatty acid metabolism and increased glucose metabolism in myocardium leading to a paial shift from FFA to glucose oxidation in the hea, which provides less ATP but requires less O2 and may therefore be beneficial in ischemia. Efficient in reducing angina and increase exercise tolerance, paicularly in patients with diabetes and hea failure.
Category:
Pharmacology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now