ELISA is performed on a population with low prevalence. What would be the result of performing double screening ELISA tests

ELISA is performed on a population with low prevalence. What would be the result of performing double screening ELISA tests –

A. Increased sensitivity and positive predictiv value

B. Increased sensitivity and negative predictive value

C. Increased specificity and positive predictive value

D. Increased specificity and negative predictive value

Correct Answer: Increased specificity and positive predictive value

Description: The specificity of ELISA can be increased by carrying out ELISA in a row (series) using different HIV markers. When screening test is used in a series mode : - ↑ Specificity ↑ PPV ↓ Sensitivity

Category: Social & Preventive Medicine

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