Non specific esterase is positive in all the categories of AML except –
Correct Answer: M6
Description: Ans. is 'd' i.e., M6 o FAB classification divides AML into eight types M 0 to M7. o This scheme takes into account : ? i) The degree of maturation (MO to M3) ii) The lineage of leukemic blast (M4 to M7). Class Blast cells o Myeloperoxidase negative Mo minimally differentiatedAML o Auer rods negative o Express myeloid lineage antigen o 3 % blasts myeloperoxidase positive M AML without differentiation o Auer rods positive o Full range of myeloid maturation MZ AML with maturation o Myeloperoxidase positive o Auer rods positive
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