Dilution segment in nephrom is:
Correct Answer: Ascending LOH
Description: The thick LOH is viually impermeable to H20, but large amounts of Na, Cl & other ions are actively transpoed from the tubule into the medullary interstitium. Thus, fluid in thick ascending loop becomes very dilute and k/a diluting segment of the nephron. Proximal tubules: = 65% of the filtered electrolytes is reabsorbed here, along with water ( osmosis & aquaporin - 1). Descending LOH: Water absorbed AQP - 1 much less permeable to Na & urea; there by increasing the osmolarity.
Category:
Physiology
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