Bilateral upper limb pulse less disease is?
Correct Answer: Aooaeritis
Description: bilateral upper limb pulseless disease is caused by aooaeritis Takayasu's aeritis (also known as, "aoic arch syndrome," "nonspecific aooaeritis," and "pulseless disease) is a form of large vessel granulomatous vasculitis with massive intimal fibrosis and vascular narrowing, most commonly affecting often young or middle-age women of Asian descent, though anyone can be affected. It mainly affects the aoa (the main blood vessel leaving the hea) and its branches, as well as the pulmonary aeries. Females are about 8-9 times more likely to be affected than males. Those with the disease often notice symptoms between 15 and 30 years of age. In the Western world, atherosclerosis is a more frequent cause of obstruction of the aoic arch vessels than Takayasu's aeritis. Takayasu's aeritis is similar to other forms of vasculitis, including giant cell aeritis which typically affects older individuals. Due to obstruction of the main branches of the aoa, including the left common carotid aery, the brachiocephalic aery, and the left subclan aery, Takayasu's aeritis can present as pulseless upper extremities (arms, hands, and wrists with weak or absent pulses on the physical examination) which may be why it is also commonly referred to as the "pulseless disease." Involvement of renal aeries may lead to a presentation of renovascular hypeension. Ref Davidson 23rd edtion pg 467
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