Which one of the following is not true regarding fibrolamellar carcinoma?
Correct Answer: Associated with HBV infection
Description: Unlike HCC, fibrolamellar Ca is not associated with HBV infection. Fibrolamellar carcinoma characteristically manifests as a large hepatic mass in adolescents or young adults. Most patients present in the 2nd or 3rd decade of life. Cirrhosis; elevated a-fetoprotein levels; and typical risk factors for hepatocellular carcinoma such as viral hepatitis, alcohol abuse, and metabolic disease are typically absent.
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