Complement is a series of impoant host proteins which provide protection from invasion by foreign microorganisms. Which one of the following statements best describes complement?
Correct Answer: Complement protects the host from pneumococcal and Haemophilus infection through complement components C1, C2, and C4
Description: Both IgG and IgM activate complement by the classic pathway, while IgA activates it by the alternative pathway. Neither IgD nor IgE can activate complement. Complement is a system of several proteins that is activated by either an immune or a nonimmune pathway. Both of these pathways result in the production of many biologically active components that cause cell lysis and death. Reference: Ananthanarayan and Paniker&;s Textbook of Microbiology Tenth edition
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Microbiology
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