Which of the following statements about Rheumatoid Factor is true –
Correct Answer: It is an IgM antibody directed against IgG
Description: Rheumatoid factor in Rheumatoid Arthritis is an IgM antibody directed against the Fc fragment of IgG
Anti CCP antibodies are most specific blood test for rheumatoid arthritis (specificity ∼ 95%).
Rheumatoid factor is positive in only 10% of patients with JRA.
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Pathology
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