Decreased plasma renin activity is seen in:
Correct Answer: Primary hyperaldosteronism
Description: Primary hyperaldosteronism is due to bilateral adrenal hyperplasia or due to adrenal adenoma. Both these conditions are autonomous and lead to aldosterone production in excess. The R.A.A.S system negative feedback will result in decrease in renin production. Low renin Hypeension is a feature of primary hyperaldosteronism. Causes of low renin hypeension Liddle syndrome Conn's syndrome Mineralocoicoid receptor mutation Apparent mineralocoicoid excess (AME) Glucocoicoid resistance Gordon syndrome Congenital adrenal hyperplasia (CAH)
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