The collagen triple helix structure is not found free in which of the following cell organelle?
Correct Answer: Cytoplasm
Description: Collagen is synthesized on ribosomes as pre-pro-collagen. From there it enters the endoplasmic reticulum where the signal sequence is removed from the terminal end and glycosylation and hydroxylation of proline and lysine residues occur, resulting in the formation of procollagen. From endoplasmic reticulum it is secreted extracellularly through the golgi apparatus. Here the extracellular enzymes cleaves the extension peptides and finally the triple helical collagen moleculs assemble into collagen fibers. Ref: Harper's Principles of Internal Medicine, 25th Edition, Page 697 and 29th Edition, Chapter 48 ; Lipppincott Biochemistry, 2nd Edition, Page 40 ; Vasudevan Biochemistry, 4th Edition, Page 240
Category:
Biochemistry
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now