A noncompetitive inhibitor of an enzyme does which of the following?
Correct Answer: Decreased Vmax
Description: Ans. A. Decreased VmaxIn Contrast to competitive inhibitors, noncompetitive inhibitors are not structural analogues of the substrate. Consequently, noncompetitive inhibitors bind to enzymes in locations remote from the active site. For this reason, the degree of inhibition is based solely upon the concentration of inhibitor and increasing the substrate concentrations do not compete with or change the inhibition. Therefore, unlike the increase in Km seen with competitive inhibition, in noncompetitive inhibition V max decreases while Km usually remains the same. While competitive inhibitors can be overcome at sufficiently high concentration of substrate, noncompetitive inhibition is irreversible.
Category:
Biochemistry
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now