BAse substitution mutations can have been following molecular consequence except

Correct Answer: Reading frame changes downstream to the mutant site
Description: A substitution is a mutation that exchanges one base for another (i.e., a change in a single "chemical letter" such as switching an A to a G). Such a substitution could:Change a codon to one that encodes a different amino acid and causes a small change in the protein produced. For example, sickle cell anemia is caused by a substitution in the beta-hemoglobin gene, which alters a single amino acid in the protein produced.Change a codon to one that encodes the same amino acid and causes no change in the protein produced. These are called silent mutations.Change an amino-acid-coding codon to a single "stop" codon and cause an incomplete protein. This can have serious effects since the incomplete protein probably won&;t function.
Category: Biochemistry
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