The earliest chest X-ray change in cystic fibrosis is:
Correct Answer: Hyperinflation
Description: The earliest chest x-ray finding in CF lungs is hyperinflation, reflecting small-airways obstruction. Later, signs of luminal mucus impaction, bronchial cuffing, and finally bronchiectasis, e.g., ring shadows, are noticed. Ref: Harrisons Principles of Internal Medicine, 18th Edition, Page 2149.
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