Medical MCQ - An i.v. bolus dose of thiopentone leads to loss of consciousness within10-15 sec. The patient regains consciousness in just a few minutes. This is because it is:

An i.v. bolus dose of thiopentone leads to loss of consciousness within10-15 sec. The patient regains consciousness in just a few minutes. This is because it is:

Renally excreted

Exhaled rapidly

Rapidly metabolised by hepatic enzymes

Redistributed from brain to other body tissues

Question Category:

Correct Answer:

Redistributed from brain to other body tissues

Description:

Thiopentone - is highly lipid soluble agent - it first reach the highly perfused organs like brain - Therefore, onset of action of these agents is very quick. However, action also terminates quickly because of redistribution to less well perfused tissues like fat and muscle.

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