Howel-Jolly bodies may be seen after ?
Correct Answer: Splenectomy
Description: Ans:B.) Splenectomy Howell-Jolly bodies They are histopathological findings of basophilic nuclear remnants (clusters of DNA) in circulating erythrocytes. Howell-Jolly bodies are seen with markedly decreased splenic function. Common causes include asplenia (post-splenectomy)or congenital absence of spleen. Other causes are radiation therapy involving the spleen, such as that used to treat Hodgkin lymphoma. Howell-Jolly bodies are also seen in: amyloidosis, severe hemolytic anemia, megaloblastic anemia, hereditary spherocytosis, heterotaxy with asplenia and myelodysplastic syndrome.
Category:
Pathology
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