In a case of vesicular mole all of following are high risk factors for the development of choriocarcinoma except:
Correct Answer: Features of thyrotoxicosis
Description: Ans. is c, i.e. Features of thyrotoxicosisRef. William 24/e, p 401Risk factors for malignant changeComplete mole (15-20% case)Patient's age >=40Serum hCG >=100,000mIU/mLUterine size >= large for gestational ageTheca lutein cysts: large (>6cm diameter)Slow decline in b-hCGSonographic appearance of myometrial nodules or hypervascularity postevacuation is also a predictor of subsequent neoplasia.From the above list it is clear that option "a" is correct.Coming on to option "d" i.e. Presence of bilateral theca lutein cyst Williams Obs. 23/e, p 259"Montz and colleagues (1988) reported that gestational trophoblastic neoplasia was more likely in women with theca-lutein cysts, especially if bilateral." (i.e. option "d" is correct).So that leaves us with 2 options 'b' and 'c'. As far as uterine size larger than 16 weeks is concerned-According to Dutta p 197 - Size of uterus >20 weeks is considered as a risk factor and not > 16 weeks, but according to other books excessive uterine enlargement is one of the risk factor- no specific size has been mentioned.As far as thyrotoxicosis is concerned I did not get any literature regarding, it being one of the risk factors.So, option 'c' is the answer of choice.
Category:
Gynaecology & Obstetrics
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now