What is the mechanism of action of Delamanid ?
Correct Answer: Inhibition of Mycolic acid synthesis
Description: DELAMANID: It is an anti-tuberculosis agent derived from the Nitro-dihydro-imidazooxazole class of compounds. MOA: Forms a reactive intermediate metabolite that inhibits Mycolic acid production. USE: In treatment of multidrug-resistant (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB) in a combination regimen. S/E: QT segment prolongation
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Pharmacology
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