Treatment of choice for squamous anal carcinoma is

Correct Answer: Chemoradiotherapy
Description: Radiotherapy with concurrent chemotherapy (Chemoradiotherapy) is the standard of care for patients with nonmetastatic squamous cell anal cancer. Most patients treated with chemoradiotherapy have an excellent prognosis. Nigro Regime :Initial radiotherapy for 3 weeks 3000 rads (30 Gy total) to perineum and pelvis. Then chemotherapy--5 FU, for 4-5 days; is a radiosensitizer, staed on 1st day of as 1000 mg/m2 continuous infusion. Mitomycin C is 15 mg/m2 as single dose on 1st day of . Reference : page 987 SRB's manual of surgery 5th edition
Category: Surgery
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