Botulinum toxin acts on:
Correct Answer: Inhibition of release of neurotransmitter
Description: (Ref: KD Tripathi, 7th ed. pg. 99)Release of Ach from nerve terminals occurs in small quanta--amount contained in individual vesicles is extruded by exocytosis.Two toxins interfere with cholinergic transmission by affecting release:# Botulinum toxin inhibits release# Black widow spider toxin induces massive release and depletionBotulinum toxin# Botulinum toxin A and B are highly potent exotoxins produced by Clostridium botulinum that are responsible for 'botulism' (a type of food poisoning). These neurotoxic proteins cause long-lasting loss of cholinergic transmission by interacting with axonal proteins involved in exocytotic release of Ach.
Category:
Pharmacology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now