Which of the following anticancer drug is excreted by lungs ?
Correct Answer: 5–Fluorouracil
Description: 5-Fluorouracil is rapidly metabolized in liver to produce biologically inactive metabolites which are eventually converted to carbon dioxide and eliminated by lungs.
Excretion of 80% of 5-FU can be accounted for by conversion to carbon dioxide within 12 hour of administration though its excretion in urine is only 15%.
Also note other drugs excreted by lungs are procainamide, procaine and antipyrine.
Category:
Pharmacology
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