True about tetanus is

A. Gram negative spore forming organism

B. Produces tetanolysin and tetanospasmin

C. Trismus and neck stiffness are early signs

D. Generalized tonic-clonic seizure occurs on hyperstimulation

Correct Answer: Produces tetanolysin and tetanospasmin

Description: C.tetani produces two distinct toxins- a hemolysin(tetanolysin) and a powerful neurotoxin9tetanospasmin). These are antigenically and pharmacologically distinct and their production is mutually independent. Ref: Textbook of microbiology; Ananthanarayan and paniker's; 10th Edition; Pg:265

Category: Microbiology

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