Renal biopsy demonstrates concentric, laminated thickening of aeriolar walls due to proliferation of smooth muscle cells. This process is BEST described by which of the following terms?
Correct Answer: Hyperplastic aeriolosclerosis
Description: The "onion skinning" morphology of these aerioles is a feature of hyperplastic aeriolosclerosis. Affected vessels may also show necrotizing aeriolitis with acute vessel wall necrosis accompanied by fibrin deposition. This type of vessel change is a hallmark of severe (malignant) hypeension, and can damage aerioles throughout the body, notably in the kidneys, intestine, and gall bladder.Atherosclerosis would produce luminal narrowing by plaques.Hyaline aeriolosclerosis would produce paial replacement of aerial walls by homogeneous, pink material.Monckeberg's aeriosclerosis is characterized by medial calcification of smaller aeries. Ref: Chandrasoma P., Taylor C.R. (1998). Chapter 20. The Blood Vessels. In P. Chandrasoma, C.R. Taylor (Eds), Concise Pathology, 3e.
Category:
Pathology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now