In polyaeritis nodosa, aneurysms are seen in all, except:
Correct Answer: Lung
Description: Answer is B (Lung): 'PAN (classic PAN) does not involve pulmonary aeries although bronchial vessels may be involved. Aneurysmal dilatation npto 1 cm in size along the involved aeries is characteristic of PAN.r-Harrison 16th/2007. Classical PAN: Review Classical PAN is a multisystem necrotizing vasculitis of small & medium sized muscular aeries in which involvement of renal & visceral aeries is characteristic Clinical Manifestations Related to Organ System Involvement in Classic Polyaeritis Nodosa Renal Hypeension, Renal failure Musculoskeletal Ahritis, ahralg a, myalgia Peripheral nervous system Peripheral neuropathy, mononeuritis multiplex Gastrointestinal tract Abdominal pain, nausea and vomiting, bleeding, bowel infarction and perforation, cholecystitis, hepatic infarction, pancreatic infarction Skin Rash, purpura, nodules, cutaneous infarcts, livedo reticularis, Raynaud phenomenon Cardiac Congestive hea failure, myocardial infarction, pericarditis Genitourm!ig Testicular, ovarian, or epididymal pain Central nervous system Cerebral vascular accident, altered mental status, seizure Remember: Classic PAN does not involve pulmonary aeries. Bronchial vessels may be involved but their involvement also, is an uncommon Jeature.Q Renal involvement is characterized by aeritis without glomerulonephritis. Clinically renal involvement is in the form of renovascular hypeension is frequent. Renal failure may occur but it is uncommon and usually occurs late.Q
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