True statement about ductus aeriosus is:

A. It undergoes anatomic closure within 24 hours of bih

B. It connects aoa with pulmonary vein

C. It is induced to close by high levels of prostaglandins

D. May cause a machinery murmur by its patency

Correct Answer: May cause a machinery murmur by its patency

Description: IMPOANT POINTS ABOUT DUCTUS AERIOSUS: - Physiological closure: occurs almost immediately after bih by contraction of muscular wall - Anatomic closure: occurs by proliferation of intima in 10-21 days after bih - After obliteration, it forms ligamentum aeriosum. - Murmur due to PDA - Continuous machinery murmur. - Ductus aeriosus is kept open with the help of prostaglandins in ductus dependent conditions Note : Prostaglandin inhibitors are used to close the ductus aeriosus. Intravenous (IV) indomethacin or ibuprofen is used to treat patent ductus aeriosus (PDA) in premature infants.

Category: Pediatrics

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