Chlonorchis sinensis infection is due to ingestion of?

Correct Answer: Fish
Description: Ans. is 'a' i.e., Fish Clonorchis sinesis Clonorchis sinensis is a trematode. It is also known as liver luke. Man is definitive host for clonorchis and snail is the secondary host. Clonorchis sinensis is caused by ingestion of metacercaria in inadequately cooked freshwater fish. The organisms excyst in the duodenum. The larva travel through the ampulla of vater and mature into adult worms in bile canaliculi. The adult worms release small operculated eggs which pass with bile into the intestines and are voided with stools. Most of the infections are asymptomatic because of the low worm burden. Chronic infection or repeated infection is associated with manifestations such as : Cholangitis Cholangiohepatitis Biliary obstruction (Biliary obstruction causes increase in alkaline phosphatase). Also know Clonorchis sinensis infection is associated with cholangiocarcinoma.
Category: Microbiology
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