The following test is an example of heterophile antigen based test-
Correct Answer: Paul Bunnel's along with HLA Class-I stimulate
Description: In infectious mononucleosis, the patient exhibits- Atypical lymphocytes in the circulating blood. - Antibodies to the EB Virus. - Increased heterophile antibody titre. The normal titre of agglutinins and hemolysins in human blood against sheep red blood cells does not exceed 1:8, but in infectious mononucleosis the titre may rise to 1:4096. This is referred to as positive Paul Bunnel test and is both characteristic and pathognomic of the disease.
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