True regarding Kaposi’s sarcoma is all except
Correct Answer: Lymph node involvement suggests worst prognosis
Description: In contrast to most malignancies, in which lymph node involvement implies metastatic spread and a poor prognosis, lymph node involvement may be seen very early in KS and is of no special clinical significance. Kaposi sarcoma causes lesions to grow in the skin, lymph nodes, internal organs and mucous membranes lining the mouth, nose and throat. It often affects people with immune deficiencies, such as HIV or AIDS. Ref Robbins 9/e pg 234
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