A patient with recurrent bacterial infections is diagnosed to have a genetic deficiency in myeloperoxidase. The cause of increased susceptibility to infections is –
Correct Answer: An inability to produce hydroxyhalide radicals
Description: Ans. is 'c' i.e., An inability to produce hydroxyhalide redicalso Myeloperoxidase in the presence of halide (C1 ) conves H202 to hypochlorite (HOCI). HOCI is a potent microbicidal agent that destroys microbes by halogenation or by oxidation of lipids and proteins. The H202 myeloperoxidase halide system is the most efficient bactericidal system in neutrophils.
Category:
Pathology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now