A 70-year-old male has a pathologic fracture of femur. The lesion appears a lytic on X-rays film with a circumscribed punched out appearance. The curetting from fracture site is most likely to show which of the following –

Correct Answer: Sheets of atypical plasma cells
Description: History,pathologic fracture, such as lytic lesion in x - ray and punched out lesion are suggestive of multiple myeloma. Even away fro ove tumour masses, the marrow contains an increased number of plasma cells.These plasma cells mah infiltrate the interstitium or be present in sheets that completely replace normal elements. On cuerreting this will be obtained. Reference; Robbins and Cotran Pathologic basis of disease.South Asia Edition volume 1.page no. 599
Category: Pathology
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