Which one of the following is FALSE about Ticlopidine?

A. Inhibits platelet function by inducing a thrombasthenia like state

B. Stimulates platelet aggregation and clot retraction

C. Prolongs the bleeding time

D. Directly interacts with platelet membrane glycoprotein IIb/IIIa receptors

Correct Answer: Stimulates platelet aggregation and clot retraction

Description: (B) Stimulates platelet aggregation and clot retraction# Aspirin, Ticlopidine, Dipyridamole are antiplatelet drugs.> Ticlopidine interacts with platelet membrane GP llb/llla & alters fibrinogen binding to platelets.> Ticlopidine inhibits platelet aggregation & clot retraction. It has no effect on TXA2, but bleeding time is prolonged.

Category: Pharmacology

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