Curschmann’s crystals are seen in –
Correct Answer: Bronchial asthma
Description: Pathology of Asthma
Gross -
Lungs are overdistended because of overinflation and there may be a small area of atelectasis.
The most striking macroscopic finding is occlusion of bronchi and bronchioles by thick tenacious mucus plugs.
Histology -
Characterized by the presence of numerous eosinophils and neutrophils.
Curschmann's spiral - Whorls of shed epithelium in mucous plugs.
Charcot -Leyden crystals - Collection of crystalloids made up of eosinophilic membrane protein.
The other characteristic histological finding of Asthma is collectively called Airway remodelling, it includes -
Thickening of the basement membrane of the bronchial epithelium.
Edema and an inflammatory infiltrate in the bronchial walls with a prominence of eosinophils and mast cells.
An increase in the size of submucosal glands.
Hypertrophy of bronchial wall muscle.
The "airway remodelling" contributes to airflow obstruction.
Category:
Pathology
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