True about protein A of staph aureus:
Correct Answer: Binds to Fc portion of IgG
Description: Ans. is 'b' i.e., Binds to Fc part of IgG(Ref: Ananthanarayan, 9th/e, p. 197, 198)* Protein A is a cell wall component of S aureus strains and is a bacterial surface protein called as microbial surface components recognizing adhesive matrix molecules (MSCRAMMs).Bacterial attachment to host cells is mediated by MSCRAMMs, and these are important virulence factors.Protein A of Staph aureus binds to Fc terminal of IgG (IgG 1, 2 and 4 but not IgG 3) and prevents opsono- phagocytosis by PMNs.* Protein A has become an important reagent in immunology and diagnostic laboratory technology; for example, protein A with attached IgG molecules directed against a specific bacterial antigen agglutinates bacteria that have that antigen ("conglutination").
Category:
Microbiology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now