Down regulation of hormone means ?
Correct Answer: Decreased affinity to receptors
Description: Ans. is 'b' i.e., Decreased affinity to receptors Down regulation is a mechanism in which a hormone decrease the number or affinity of its receptors in target tissues. Down-regulation may occur by decreasing the synthesis of new receptors, by increasing the degradation of existing receptors or by inactivating receptors. The purpose of down-regulation is to reduce the sensitivity of the target tissue when hormone levels are high for an extended period of time.
Category:
Physiology
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