Causes of metabolic alkalosis include all the following except –
Correct Answer: Mineralocorticoid deficiency
Description: Mineralo corticoid deficiency is a cause normal anion gap metabolic acidosis-
Recurrent vomiting
Gastro intestinal loss of H+ from repeated vomitings results in retention of HCO3- and hence metabolic alkalosis
Thiazides
Thiazides are diuretics which acutely diminish the ECF volume without altering the total body bicarbonate
The serum Bicarbonate concentration, therefore, increases and hence metabolic alkalosis
Bartter's Syndrome
Bartter's syndrome is characterized pathologically by impaired Cl- reabsorption in the thick ascending loop of Henle and clinically by a triad of
Metabolic alkalosis
Hypokalemia
Normal or low B.P.
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