A female presents with history of progressive breathlessness. Histology shows heterogenous patchy fibrosis with several fibroblastic foci. The most likely diagnosis is:

Correct Answer: Usual Interstitial Pneumonia
Description: Histologic hallmark of UIP is a heterogeneous appearance at low magnification with alternating areas of normal lung, interstitial inflammation, foci of proliferating fibroblasts, dense collagen fibrosis and honeycomb changes. Ref: Harrison's Principles of Internal Medicine, 16th Edition, Page 1557.
Category: Pathology
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