The TRUE statement about B cell Prolymphocytic leukemia is:
Correct Answer: The cell express surface IgM and CD19,20,22
Description: B Cell Prolymphocytic Leukemia Malignancy of medium-sized, round lymphocytes with a prominent nucleolus and light blue cytoplasm It usually does not cause adenopathy. The median age of patients is 70 years The clinical course can be rapid. The cells express surface IgM and B cell markers (CD19, CD20, CD22). CD23 is absent. Fludarabine and cladribine and combination chemotherapy (cyclophosphamide, doxorubicin, vincristine, prednisone, or CHOP) are effective. Splenectomy can produce palliation of symptoms but little impact on the course of the disease. Ref: Harrison, E-18, e-21.
Category:
Medicine
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now