Characteristic skin lesion in Peutz -Jeghers syndrome is
Correct Answer: Lentigens
Description: Peutz Jegher syndrome. Peutz-Jeghers syndrome- Autosomal dominant - Lentigens (increased melanocytes leading to hyperpigmented macules) - Site of lentigen - Perioral(lips),Buccal mucosa - Associated with GI polyp. (MC : Jejunal hamaoma)Freckles /ephelides* It is increased localized melanogenesis.* Normally seen in fairer skin colour (Skin type I,II)* Become dark on sun exposure Adenoma Sebaceum is seen in Tuberous sclerosis aka epiloia Cafe au lait macules is seen in Neurofibromatosis (dark color lesion over lighter skin).
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