In a 40-year-old woman receiving TPN for small-bowel fistula, what finding can be attributed to hypophosphatemia?
Correct Answer: Rhabdomyolysis
Description: Hypophosphatemia results in decreased synthesis of phosphorylated intermediate metabolites such as adenosine triphosphate (ATP), 2, 3-DPG, and cyclic adenosine monophosphate (cAMP). Deficiency can result in erythrocyte membrane instability, WBC dysfunction, platelet dysfunction, congestive hea failure, arrhythmias, weakening of respiration muscles, hemolysis, and rhabdomyolysis.
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