Action of Papain on an IgG molecule produces?
Correct Answer: 1 Fc fragment & 2 Fab fragments
Description: 1 Fc fragment & 2 Fab fragments REF: Jawetz, Melnick, & Adelberg's Medical Microbiology, 24TH edition Chapter 44 If an antibody molecule is treated with a proteolytic enzyme (eg, Papain), peptide bonds in the hinge region are broken. This breakage produces two identical Fab fragments, which carry the antigen-binding sites, and one Fc fragment, which is involved in placental transfer, complement fixation, attachment for various cells, and other biologic activities.
Category:
Microbiology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now