Which microorganism is responsible for classical presentation of hydrocephalus, chorioretinitis, intracerebral calcification ?
Correct Answer: Toxoplasmosis
Description: Ref: Parija SC, Textbook of Medical Parasitology. 3rd Edition. London: John Wiley & Sons: 2004. Pg. 175 Explanation: Toxoplasma Gondii It is an obligate intracellular parasite, residing in reticulendothelial cells and nucleated cells of the host. Three major morphologic forms are present (All forms are infectious) Tachyzoites - Humans and cats Tissue cyst - Humans and cats Oocyst - Cats only Congenital toxoplasmosis It occurs when a non-immune pregnant woman becomes infected during pregnancy It is due to transplacental transmission of the tachyzoites If the infection occurs during first trimester, it can result in deg Abortion or Stillbirth (Most common) deg Congenital toxoplasmosis (17%) If infection occurs during last trimester, the symptoms are mild and the babies may be asymptomatic at birth. About 65% of the babies suffer from congenital toxoplasmosis due to infection during last trimester. The classical clinical triads of congenital toxoplasmosis are: deg Chorioretinitis deg Cerebral calcifications deg Convulsions. Microcephaly, hydrocephalus, organomegaly and mental retardation are the less frequent manifestations.
Category:
Pediatrics
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now