If chymotrypsin molecule undergoes a ser-195-ala mutation then :
Correct Answer: Chymotrypsin will bind the substrate but will not cause cleavage
Description: Serine- 195 is a highly reactive residue of chymotrypsin molecule.It endows chymotrypsin with its 'Reactivity' and not its ability to bind to substrate. In absence of Ser- 195 residue, chymotrypsin is inactivated i.e., it will not cleave, however, it still has the ability to bind (by viue of other remaining residues).
Category:
Biochemistry
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