A 55-year-old female patient presents with duodenal ulcer. The most sensitive test to detect Helicobacter pylori is
Correct Answer: Urea breath test
Description: Urea breath test is the most sensitive test for diagnosis of Helicobacter pylori infection. Urea breath test: The patient drinks a solution of urea labeled with a radioactive Carbon-14 and then blows into a tube. If H. pylori urease is present, the urea is hydrolyzed, and labeled carbon dioxide is detected in breath samples. Reference: Ananthanarayan and Paniker&;s Textbook of Microbiology Tenth edition
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Microbiology
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