Blood nerve barrier is formed by:
Correct Answer: Perineurium
Description: Ref: Histology a Text and Atlas, 6th edition, Michael H. Ross, Page 376Explanation:"Together with endothelial cells of blood vessels within the fascicle, perineurial cells constitute part of the blood-nerve barrier, an important andselective diffusion barrier against entry of potentially infectious and toxic substances that may alter normal function of the nerve." Ref: Netter's Essential Histology by Ovalle WK, 2nd edition. Page 130"Tight junctions, providing the basis for the blood- ner!e barrier, are present between the cells located within the same layer of the perineurium. " Ref: Histology by Ross MH, 5th edition. Page 342"The perineurium has the character of an epithelium, called perineurial epithelium, and functionally contributes to the formation of a blood- nerve barrier (blood-brain barrierRef: Functional Ultrastructure: Atlas of Tissue Biology and Pathology By Margit Pavelka, Page 324BLOOD NERVE BARRIERFormed by Perineurium of Peripheral Nerves and the endothelium of endoneurial Capillaries.The perineurium acts as a diffusion barrier.but ion permeability is higher than at the blood- brain barrier.ALSO NOTEBlood Brain Barrier (BBB)Formed by:o Tight junctions of endothelial cellso Foot process of the astrocytes around the capillaries.Filters only Lipid soluble substances.Areas outside BBB--Collectively known as Circumven-tricular organs: (Mnemonic-M. SOAP)o Median eminenceo Sub fornical organo Organum vasculosumo Area postrcmao Posterior pituitary.
Category:
Physiology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now