All of the following drug is CYP3A inhibitor except:
Correct Answer: Saquinavir
Description: Ans. D. SaquinavirOut of all protease inhibitors, Saquinavir has least effect on hepatic microsomal enzymes. Rest of the protease inhibitors inhibit microsomal enzymesImportant enzymes inhibitors:a. Acute alcohol intakeb. Sodium valproatec. Cimetidine, Ketoconazole, Erythromycind. Grape fruit juicee. Protease inhibitors (Pls)f. Fluoroquinolonesg. Omeprazole
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