Fluroquinolone mechanism of action in gram positive organism is by ?
Correct Answer: Topoisomerase IV
Description: Ans. is 'd' i.e., Topoisomerase IV Fluroquinolones Fluoroquinolones (including ciprofloxacin) inhibit DNA gyrase and topoisomerase IV. For gram negative bacteria, the primary target is DNA gyrase, while topoisomerase IV is inhibited in gram positive bacteria.
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