A 37-year-old immunosuppressed patient with renal failure develops sepsis. Which of the following antibiotics, if used, would require a major reduction in dosage?
Correct Answer: tobramycin
Description: Amikacin and vancomycin are the other antibiotics that require dose reduction in renal failure. Newer antibiotics are often used instead of aminoglycosides to reduce the risk of renal damage.
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