Sweat chlorides are increased in:

Correct Answer: Cystic fibrosis
Description: The diagnosis of CF rests on the combination of clinical criteria and abnormal CFTR function as documented by sweat tests, nasal PD measurements, and CFTR mutation analysis. Elevated sweat Cl- values are nearly pathognomonic for CF. The sweat concentration values for Cl- (and Na+) vary with age, but, typically, a Cl- concentration of >70 meq/L in adults discriminates between CF and other lung diseases. Ref: Boucher R.C. (2012). Chapter 259. Cystic Fibrosis. In D.L. Longo, A.S. Fauci, D.L. Kasper, S.L. Hauser, J.L. Jameson, J. Loscalzo (Eds), Harrison's Principles of Internal Medicine, 18e.
Category: Biochemistry
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