A 15-year-old female presents with primary amenorrhea. Her breasts are normally developed but she has no axillary or public hair The most likely diagnosis is
Correct Answer: Testicular feminization syndrome
Description: Testicular feminizing syndrome
Genotype is 46XY, Phenotype is female
The gonads are testes often present in the inguinal canal.
Gonads produce testosterone and Mullerian inhibiting substance, but because of androgen insensitivity at target organs, Patients have
Lack of axillary and pubic hair and normally developed breasts
Absent uterus and upper vagina
May have a blind pouch of lower vagina
Category:
Gynaecology & Obstetrics
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