Which of the following agent is a rho kinase inhibitor?
Correct Answer: Fasudil
Description: Ans. (A) Fasudil(Ref: Katzung 12th/e p206)*Rho kinase (ROCK) is a major downstream effector of the small GTPase RhoA. ROCK plays central roles in the organization of the actin cytoskeleton and is involved in a wide range of fundamental cellular functions such as contraction, adhesion, migration, proliferation and gene expression.*Fasudil is an experimental drug that acts by inhibiting the rho kinase and is found to be effective in animal models for treatment of-Hypertension-Pulmonary Hypertension-Coronary artery disease-Diabetic cardiomyopathy-Vasospastic angina-Ischemic stroke-Heart failure-Erectile dysfunction-Cardiac remodeling
Category:
Pharmacology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now